Peter Reynolds

The life and times of Peter Reynolds

CLEAR and GroGlo Establish First UK Clinical Trials on Cannabis for Chronic Pain.

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CLEAR has formed a partnership with the research arm of GroGlo, a UK-based manufacturer of high power, LED, horticultural grow lighting.

The plan is to grow cannabis under a Home Office licence for the production of cannabis oil, both as a dietary supplement and for the development of medical products.  To begin with, a low-THC crop of industrial hemp will be planted.  We will be using the finola strain, originally developed in Finland and known for its short stature and early flowering. Unlike hemp grown for fibre, finola is usually grown for seed and only reaches a height of 160 – 180 cm but we will be removing male plants before they produce pollen and cultivating the female plants to produce the maximum yield of oil from their flowering tops.

Finola Industrial Hemp

Finola Industrial Hemp

The low-THC oil will be marketed as a dietary supplement, commonly known as CBD oil. There is already a burgeoning market in the UK for CBD products, all of which is currently imported from Europe or the USA.  In the USA, the CBD products market was said to be worth $85 million in 2015 so there is huge potential here at home. Aside from the benefit of being UK grown and processed, we anticipate achieving a CBD concentration of about 40%, which is higher than most products already on the market.

Cultivation will be in glasshouses supplemented with LED lighting.  GroGlo already has an established glasshouse facility in the east of England.  Initial trials will experiment with adjusting the LED technology to provide a changing blend of light wavelengths at different stages of plant growth.  This is GroGlo’s area of expertise -combining LED lighting and plant sciences, including existing relationships with some of Europe’s top universities. Professor Mick Fuller, GroGlo’s director of plant science, will lead this research and development process.

Professor Mick Fuller

Professor Mick Fuller

During the R&D phase, CO2 extraction of oil will be carried out under laboratory conditions at universities in York and Nottingham which already have extensive experience of the process. Each crop will be measured for yield, cannabinoid and terpene content using high pressure liquid chromatography (HPLC).  Safety testing will also look for the presence of heavy metals and other contaminants.  The results of testing will be fed back into cultivation and extraction processes to maximise yield and quality.

It is anticipated that the first batches of low-THC oil will be ready for market in six months.  We are already in discussions with potential distributors and wholesalers. The CBD market in the UK is ripe for an effective marketing campaign which could build a very substantial business for whoever gets it right.

Once we are successfully achieving our production goals with low-THC cannabis, the same testing and development process will begin with high-THC varieties of cannabis.  The aim will be to produce a range of oils extracted from single strains, selectively bred and stabilised for different THC:CBD ratios.

Professor Fuller says that GroGlo lighting products “are in use worldwide to grow a range of crops, but some 60% of sales currently come from overseas users growing cannabis for legitimate medical use.”  He explains that there is an emerging market for all sorts of nutritional and medicinal plant products but cannabis shows particular promise. GW Pharmaceuticals is the only UK company to enter this market and it has become a world leader, despite the current restrictive legislation.  He says:  “Together with CLEAR we believe we can help bring a range of safe, high quality UK-produced cannabis products to market within a matter of two to three years.”

A key issue in the development of a successful medicinal cannabis product is the method of delivery.  Smoking is not an acceptable solution as inhaling the products of combustion is an unhealthy practice but one of the great benefits of cannabis smoked as medicine is very accurate self-titration.  That is the effects of inhaled cannabis are felt almost instantly and so the patient knows when they have taken enough or when they need more to achieve the required analgesic effect.

The oral mucosal spray developed for Sativex is unpopular with patients, many complain of mouth sores from its use and it was developed at least as much with the objective of deterring ‘recreational’ use of the product as with delivering the medicine effectively. It strangles the therapeutic benefits of the cannabis oil of which Sativex is composed in order to comply with the concerns of the medicines regulators about ‘diversion’ of the product into what they would term ‘misuse’.  Absorption of the oil is quicker through the mucous membranes of the inside of the mouth than through the gastrointestinal system but, inevitably, some of the oil is swallowed and the pharmacology of cannabis when processed through the gut and the liver is very different.

We believe the best option is a vapouriser device and our intention is to source a ‘vape pen’ of sufficient quality to operate within clinical standards of consistency and safety. Vapourising cannabis oil avoids inhaling the products of combustion but still enables accurate self-titration of dose.  A vape pen would provide a handy, convenient and very effective method of consuming medicinal cannabis.  However, aside from the technology itself, initial research shows that vapour is more effectively produced when the oil is blended with either vegetable glycerin (VG) or propylene glycol (PG).  Establishing the correct ratio of VG or PG to the oil is another important task.

We anticipate that clinical trials for the use of cannabis oil in treating chronic pain could start within two years.  We want to compare different oils, ranging from high-CBD to equal ratios of THC:CBD and high-THC content. Prior to that we have to overcome the challenges of cultivation, oil extraction, vapouriser development and assemble the necessary research team and gain ethical approval for the trials.  Recruitment for the trials will start in about 18 months time.  If you wish to be considered please email ‘paintrials@clear-uk.org’ with brief details of your condition (no more than 100 words). Do not expect to hear anything for at least 12 months but your details will be passed to the research team as a potential candidate.

Mike Harlington, Managing Director of GroGlo

Mike Harlington, Managing Director of GroGlo

CLEAR is promoting this venture simply because someone needs to do something to make this happen. For all the campaigning and lobbying of MPs and ministers, at the end of the day, the plants have to be grown and the various legislative hoops have to be jumped through. We cannot wait any longer for a radical change in the law. We have to progress through the government’s regulatory regime if we want to bring real therapeutic benfit to patients.

This opportunity arises because of the vision of GroGlo’s managing director, Mike Harlington and the team of experts he has built around him. There is huge demand for legitimate medicinal cannabis products in the UK which is only going to increase with the inevitable progress towards law reform and increasing awareness of the benefits of cannabis. Together, CLEAR and GroGlo are bringing the great hope that medicinal cannabis offers closer to reality than ever before.

 

Complaint Against Mike Hall, West Midlands Police ‘Cannabis Disposal Team Manager’.

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It’s becoming more common for police forces to launch publicity campaigns about their cannabis law enforcement activities.  They may be seeking to justify their expenditure or, perhaps, appease the sort of members of the public who have their Crimestoppers ‘scratch ‘n’ sniff card to hand and turn in their neighbours for growing a few plants.  To be fair, there is anti-social behaviour around some farms: destruction of rental property, theft of electricity, human trafficking, fire risks and street dealing.  These are real social harms that the police do need to deal with.  Of course they would all be virtually eliminated by a legally regulated market and the police could get on with tackling real crime.

West Midlands Police are the latest force to join up with a local media outlet to look in detail at their cannabis operations, in this case the Wolverhampton Express & Star, the biggest-selling regional evening newspaper in Britain.

Mike Hall

Mike Hall

Earlier in April a series of articles were published, all based around the ‘Cannabis Disposal Team Manager’, Mike Hall.  To those who follow UK cannabis stories he is a familiar figure who is often quoted in Midlands local newspapers.  He shares some characteristics with other police officers involved in cannabis operations, a bit like PC Adge Secker of Avon and Somerset Police, against whom CLEAR is already successfully pursuing a complaint.  They seem to be publicity hungry, truculent and rather cocky. They consider themselves as experts, when their knowledge is actually very weak, and they seem to think they can use fear, scaremongering, exaggeration and express their personal political opinions in their official capacity.

They can’t. In fact, engaging in politics amounts to misconduct for a police officer.

We have submitted a formal complaint to the Professional Standards department of West Midlands Police.

From: Peter Reynolds
Sent: 20 April 2016 14:40
To: ‘contactus@west-midlands.pnn.police.uk’
Subject: Attention Professional Standards Department. Complaint against Mike Hall, cannabis disposal team manager.
Importance: High

Dear Sirs,

1. I wish to make a complaint against Mike Hall, cannabis disposal team manager.

I make the complaint on my own account but also in my capacity as the president of CLEAR Cannabis Law Reform of Kemp House, 152 City Road, London, EC1V 2NX. For the purposes of correspondence, please contact me via email.

2. Hall has been in engaging in politics by giving interviews to the Express and Star about cannabis which amount to politicking, propaganda, misleading and terrorising the public. The interviews can be seen at these links :

Published Apr 9, 2016. VIDEO. “Exclusive look inside a mock cannabis factory” https://youtu.be/kgpUsypBjhY

Published April 10, 2016 “Sowing the seeds of drugs: The easy-to-buy items that harbour a hidden secret”: http://www.expressandstar.com/news/2016/04/10/sowing-the-seeds-of-drugs-the-easy-to-buy-items-that-harbour-a-hidden-secret/

3. Police officers are specifically prohibited from engaging in politics by schedule 1 of the Police Regulations 2003 which states:

“A member of a police force shall at all times abstain from any activity which is likely to interfere with the impartial discharge of his duties or which is likely to give rise to the impression amongst members of the public that it may so interfere; and in particular a member of a police force shall not take any active part in politics.”

4. I am a victim of misconduct by Hall which has caused me distress at his misuse of his office to promote myth, prejudice and propaganda about cannabis and hatred of cannabis users as a social group. I am also acting on behalf of more than half a million registered supporters of CLEAR who are victims of Hall’s misconduct for the same reasons, particularly those who need cannabis as medicine for the treatment of conditions such as MS, Crohn’s disease, fibromyalgia, spinal injury, epilepsy and chronic pain. Hall has specifically attacked people suffering from arthritis with grossly offensive, defamatory and inaccurate claims.

5. In the video linked to in 2. above, starting at approximately 2:42, Hall says:

“Cannabis causes a lot of harm to the community. People talk about legalising and taxing it. From my point of view, I know that alcohol and tobacco are legalised and taxed but it doesn’t stop crimnals from profiting from counterfeiting and smuggling those commodities. There will always be crime linked to cannabis. If it was sold and legislated against there would still be underground users and growers that would be profiting from that legislation.

From my perspective and I’m an expert witness for cannabis for the purposes of the courts as well, I know that anybody who starts getting involved in cannabis it’s only a matter of time before, either out of jealousy or concern or spite, somebody lets the authorities know that you are growing cannabis. Now that can either result in the police coming round your house and you obtaining a crimnal conviction or, even worse, other people can find out and come and be armed raiders at your house to steal your cannabis. None of it is a good idea.”

6. It is incorrect to claim that “cannabis causes a lot of harm to the community”. The harms are caused not by cannabis itself but by enforcement of the law against it and would be exactly the same were basil, oregano or tomatoes prohibited. Hall’s expression of his opinions about legalising and taxing cannabis is clearly engaging in politics. His attempt to scare people about armed raiders is reprehensible. Police officers should not be terrorising the public with such exaggeration, falsehood and distortion. Hall is entitled to hold his political opinions but he is not entitled to express them in an official capacity. I recognise that cannabis is a controversial subject and people will hold different opinions but it is wholly wrong and unprofessional for any police officer to engage in this political debate and amounts to misconduct.

7. In the article linked to in 2. above, Hall is quoted as saying “We hear people talk about medicinal cannabis to help with arthritis, but then they are climbing up into their loft every three hours to water their plants.”. This is offensive to people who have arthritis and discriminates against them based on their medical condition. It is also manifestly ridiculous and inaccurate. Watering any type of plant every three hours would kill the plants. Also, modern medical practice is that people with arthritis are encouraged to keep moving. There is a great deal of peer-reviewed, published, scientific evidence that supports the safety and efficacy of using cannabis for chronic pain conditions. See attached document ‘Medicinal Cannabis:The Evidence’. Therefore, Hall’s remarks towards people with arthritis amount to misconduct.

8. Later in the article, Hall again engages in political debate. In response to the Liberal Democrat’s proposals for a regulated cannabis market, he is quoted as saying:

“It would impact on other legislation. We have relatively new laws on drug driving, but would we want the battle we have had with drink driving for decades to happen all over again? It could mean 30 years of hard publicity and no end of terrible accidents to get that through to people. You also have to ask what would happen to the thousands of unemployed drug dealers. They would turn to other areas of crime. And underground growers could profit further, as their product would not carry the tax and VAT of legal cannabis. Legalisation would not destroy the market for illegal cannabis. Tobacco and alcohol are legislated against but it doesn’t stop criminals from smuggling or counterfeiting.”

This is blatant politicking. Hall is engaging in politics in his official capacity which amounts to misconduct.

I would be grateful if you would deal with this complaint at your earliest convenience. I shall be happy to provide any further information required or to give oral evidence in support.

Yours faithfully,

Peter Reynolds

The CLEAR Executive Committee

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Following recent changes, the CLEAR executive committee is now comprised of the following people.

Andrea ClarkeAndrea Clarke

Membership Manager

 

 

 

 

 

Vicky HodgsonVicky Hodgson

Medicinal Users Panel

Vicky was awarded a fellowship of CLEAR in August 2014

 

 

 

 

 

Peter ReynoldsPeter Reynolds

President

 

 

 

 

 

Graham SmithGraham Smith

Graham was awarded a fellowship of CLEAR in July 2015

 

 

 

 

 

 

 

Derek WilliamsDerek Williams

Derek was awarded a fellowship of CLEAR in February 2014.
He is presently on compassionate leave caring for his mother who is gravely ill.

Written by Peter Reynolds

April 13, 2016 at 6:57 pm

The CLEAR Cannabis Law Reform Campaign.

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CLEAR home page regulation slider

In five years, CLEAR has transformed the UK cannabis campaign from a ragtag group of protestors into a coherent, science and evidence-based strategy. New groups pursuing similar, responsible advocacy have emerged such as the United Patients Alliance (UPA) and most recently End Our Pain (#EndOurPain).  In the last three years, in government and Parliament, there has been more liaison between the campaign, ministers and senior politicians than in the last 50 years.  The Liberal Democrats have formally adopted policies which are almost identical to those enshrined in CLEAR’s aims and objectives.

Fundamental to CLEAR’s work has been the publication of evidence and the development of plans based on consultation with consumers, patients, doctors, scientists, academics and other experts.

These three publications form the basis for all our work.  Please download them, read them, share them and use them as widely as you can.  Together they defeat all the arguments for the continuing ban on cannabis.

ttukcm thumbnailTaxing the UK Cannabis Market

The most authoritative, independent, expert research on the UK cannabis market by the Independent Drug Monitoring Unit, commissioned by CLEAR in 2011.

 

 

 

 

 

htrcb thumbnailHow To Regulate Cannabis In Britain

This is the second version of a plan for the regulation of the cannabis supply chain in Britain. This version was published on 18th October 2013

 

 

 

 

 

mcte thumbnail fcMedicinal Cannabis: The Evidence

The most up-to-date, comprehensive analysis of the evidence on the safety and efficacy of cannabis as medicine. Focuses on Alzheimer’s disease, cancer, chronic pain, Crohn’s disease and multiple sclerosis. Published April 2015.

Cancel All Foreign Aid, Get Out Of The EU And Look After My People!

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Port Talbot Steelworks

Port Talbot Steelworks

If it wasn’t for the miners and steelworkers of South Wales, the UK would now be a province of the Third Reich.  As it is, the disastrous  incompetence of  the last Labour government, topped off by out-of-touch toffs has brought us to the point where if we stay in the EU, we will be just a subsidiary of Frau Merkel’s Greater Germany.

Call them Keystone Cops, Bullingdon Club Blaggers or Carry on No 10, the loons that sit round the cabinet table in Downing Street have failed this country and should be sent packing back to their country seats. They have no idea what Britain really is and even less how to lead us into an uncertain future.

The ramifications of South Wales steel pervade our economy and our society.  It has made Britain great while Blair, Brown, Cameron and the self-serving political elite have diminished us in every way: financially, socially and morally.  We are a shadow of our former selves. We must wrest back control from these idiots.  They are an exact parallel with overpaid Premier League footballers: utterly selfish, egotistical to the ultimate, irresponsible of everything that does not benefit them directly and despised except of the power they hold. Footballers have their brains in their feet.  Our political leaders have their brains in their wallets, pension funds and the sinecures they will acquire when they leave office.

My grandfather was a South Wales steelworker.  It was career progress after he first went down the mines at age 14.  In 1938, my father was malnourished with rickets because he didn’t have enough food to eat.  It was only that year with the build-up to war that grandad had regular shifts and the family could be properly fed. Later my father won a scholarship to Oxford.  In the 80s and 90s he became one of the top commercial lawyers in the City and independently wealthy.  He was the archetypal boy from the valleys made good.  Such is the way that South Wales steel has built Britain and not just with girders, RSJs and driving piles for foundations.  It goes much deeper than that in ways that many of the Eton-educated wasters and ponces can never understand.

We must look after our own first.  It is ludicrous that we have thousand using foodbanks, we’re cutting benefits for disabled people and meanwhile we’re giving £12 billion a year away in foreign aid, £300 million to India which spends its own money on a space programme! We also pay £13 billion each year to the EU. We have to stop this madness.

Any independent nation of significance must have its own steel manufacturing capability. We are the fifth biggest economy in the world.  Save our steel industry by nationalising it.  It’s not socialism, it’s common sense.

Written by Peter Reynolds

April 6, 2016 at 3:44 pm

Personnel Changes At CLEAR.

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Roland Gyallay-Pap has resigned as managing director of CLEAR.

Roland contributed significantly to the development of CLEAR and was a valued colleague.  We are saddened by his departure and wish him well for the future.

Douglas Fraser has also left his position in charge of CLEAR’s IT systems and it will be no surprise that this is connected with the current offline status of the CLEAR website.  Such behaviour is regrettable but we have already regained control of our domain.  If the website itself is destroyed by malicious action we will simply have to make alternative arrangements.  Various other CLEAR accounts have also been hacked but we are steadily regaining control and expect everything to be resolved within the next day or so.

Written by Peter Reynolds

April 4, 2016 at 4:50 pm

Posted in Uncategorized

CLEAR Website

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I regret to inform you that the CLEAR website has been hacked in a malicious attack.

We are taking steps to regain control and further updates will be provided here

Written by Peter Reynolds

April 3, 2016 at 11:50 am

Posted in Uncategorized

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