Archive for the ‘Business’ Category
The subject of cannabis as medicine is certain to rise to the top of the UK news agenda in forthcoming weeks as a new Coronation Street storyline unfolds.
The character Izzy Armstrong (Cherylee Houston) who has Ehlers-Danlos Syndrome, will be seen suffering when her prescription medicine fails to alleviate her pain. Erica Holroyd (Claire King) will then suggest that she starts using cannabis as an alternative and ends up supplying Izzy with the drug. The programme will look at all aspects of the debate on medicinal cannabis and examine the legal implications and the far reaching consequences of Izzy’s actions for her family.
Now, three of the UK’s most important organisations in the field are joining forces to provide the media with facts, evidence and personal testimonies about medicinal cannabis.
CLEAR is the largest drugs policy reform group in the UK with nearly 600,000 followers. The British Medicinal Cannabis Campaign (BMCC) is an independent group consisting of 4,500 members, all of whom are UK-based medicinal cannabis users. UK CBD is the leading distributor of legal, cannabinoid nutraceuticals including the world famous Charlotte’s Web and Mary’s brands.
Roland Gyallay-Pap, managing director of CLEAR, commented:
“Not for the first time, but at a crucial time in the worldwide debate, the issue of medicinal cannabis will be addressed in a British soap. We have high hopes that this will stimulate the debate and bring the absurdity of the UK government’s position into sharp focus.”
Throughout Europe, the USA, Canada, Australia, Israel and South America, interest in and the use of medicinal cannabis is growing fast. The UK is now virtually isolated amongst first world countries with the stubborn refusal of government even to consider the evidence. However there is a growing clamour from politicians, scientists and doctors that it must address what is a deeply cruel and evidence-free policy. Hundreds of thousands already use medicinal cannabis and risk a criminal record just for trying to improve their health. In addition they have to deal with a criminal underworld and risk violence, contaminated and low quality product all because government refuses to take responsibility.
There is now an overwhelming body of peer-reviewed, scientific evidence on the safety and efficacy of cannabis as medicine. CLEAR published ‘Medicinal Cannabis: The Evidence’ in April 2015 which has received international acclaim and is now also available in a Spanish language edition. Download here in English or Spanish.
Individual briefings will be available on request to journalists, reporters, media organisations and other interested parties. Briefings will be led by Peter Reynolds, one of the nation’s leading experts on the science, medicine and politics of cannabis, Mark Scott, a representative of BMCC and Nicolas Ellis, founder and managing director of UK CBD.
Please contact CLEAR to arrange a briefing at your premises by appointment. Alternatively, a central London venue can be arranged on request.
I find it inconceivable that any sane human being can even consider expansion at Heathrow. The idea of increasing the traffic over what is already a hellhole, already unfit for human habitation, is madness.
The sickening amount of money pumped into the campaign to expand Heathrow raises very unusual feelings in me. It repels me and turns me against business. If this is the result of the profit motive then it is sickening, disgusting and demeans everyone involved.
I think those who advocate expanding Heathrow have slipped into a form of mental illness where common sense is overwhelmed by greed. But I think they’re wrong. It cannot be a wise decision on any basis. The cost is far, far too great.
I’m with Boris and a brand, spanking new mega airport in the Thames Estuary. It is an investment that will enrich our country, that will create so many jobs over so many decades that it can only be a winner. It is the only rational decision.
One of these vape pens contains Blue Dream sativa cannabis oil, 91% THC, the other is Hindu Kush indica cannabis oil, 85% THC and the spare cartridge has the dregs of some New York City Diesel sativa, 85% THC. You can’t tell which is which to look at them but each has a distinctive flavour and effect. They’re not completely odour free but almost.
This is the future of cannabis as a consumer product. It is cleaner, neater, handier, healthier and better for you than raw herbal cannabis. Most importantly, for medicinal applications, it homogenises all the compounds into an oil of consistent quality and content meaning that dosage and effect at last becomes predictable and reliable.
I have been investigating this theory for some time but my recent trip to Colorado enabled me to conduct some practical experiments and more thoroughly understand how this idea can work. I am now convinced that this is the way forward for the cannabis industry. Once we achieve legalisation in the UK, which is inevitable, probably in about five years, these pens are how cannabis will become available as a consumer product on the high street. They are also how medicinal cannabis will be dispensed. Your doctor’s prescription will be fulfilled by a cartridge with the appropriate blend of cannabinoids which you screw onto your battery and use immediately. Batteries will also be supplied on prescription, in the same way that syringes or blood glucose meters are for diabetics.
In Colorado dispensaries these pens are already available in a choice of strains and blends. Currently, the popular products contain 250 mg of THC in a blend of cannabis oil and propylene glycol (PG), just as e-cigs contain a nicotine oil and PG.
Alternatively, you can buy the oil of your choice and fill the cartridges yourself. This is undoubtedly the way to do it and a wide choice of oils is available, made by CO2 and solvent extraction processes. The Farm, my favourite dispensary in Boulder, is already supplying cannabinoid blends such as a 60% CBD, 12% THC, 4% CBN product which is clearly for medicinal use. I have no doubt that soon we will see a Charlotte’s Web product and Sativex-like blends with equal ratios of THC:CBD. Other, more sophisticated blends of other cannabinoids and probably terpenes will soon follow.
However, I am certain that some propylene glycol is a good thing. The oil vapes much better when diluted and PG is nothing to worry about, it is in many health, cosmetic and food products. It has many uses. It’s a solvent, humectant (keeps things moist), preservative and it helps absorption of some products. It is non-toxic.
There is further development work to be done. I believe there is a ‘sweet spot’ for the correct amount of PG, probably around 20%. I also think the battery and cartridges can be improved, particularly for medical use. Once this is achieved, a product like this with perhaps a 60:40 THC:CBD ratio should form the basis of an application to the Medicines and Health products Regulatory Agency (MHRA) for a marketing authorisation. It will knock Sativex into a cocked hat. In fact, if GW Pharma aren’t investigating this already then they are failing in their duty to shareholders. I shall certainly be doing all I can to research and facilitate the funding to bring such a product to market.
Yes, this is the future of cannabis. Imagine the packaging, marketing and merchandising opportunities for the recreational market. Understand the overwhelming benefits of this as medicine against the raw, herbal product. Yes, I know some will object and the tired old hippy luddites will say it’s a sell out and many more Big Pharma conspiracy theories will emerge but this is the future. Remember you heard it here first.
The prohibition of cannabis has caused massive harm to our society. It has created a criminal market which has attacked our children, our communities, our health and our liberty. The time to end this failed experiment is now.
Cannabis in West Sussex, England, UK. With acknowledgement and thanks to Joni Mitchell and Eddie Mitchell of Aerial News. (No relation, as far as we know)
I came upon a child of God
He was walking along the road
And I asked him where are you going
And this he told me
I’m going on down to Yasgur’s farm *
I’m going to join in a rock ‘n’ roll band
I’m going to camp out on the land
I’m going to try an’ get my soul free
We are stardust
We are golden
And we’ve got to get ourselves
Back to the garden
Then can I walk beside you
I have come here to lose the smog
And I feel to be a cog in something turning
Well maybe it is just the time of year
Or maybe it’s the time of man
I don’t know who I am
But you know life is for learning
We are stardust
We are golden
And we’ve got to get ourselves
Back to the garden
By the time we got to Woodstock
We were half a million strong
And everywhere there was song and celebration
And I dreamed I saw the bombers
Riding shotgun in the sky
And they were turning into butterflies
Above our nation
We are stardust
Billion year old carbon
We are golden
Caught in the devil’s bargain
And we’ve got to get ourselves
back to the garden
© Siquomb Publishing Company
The preposterous response from the UK government to the massive petition for the legalisation of cannabis is a pack of lies.
Yes. Lies. Not a word it’s wise to use unless it’s accurate but in this case it is. The Home Office is disgraced on so many aspects of its work but it has been systematically misleading, misinforming and promoting untruths about cannabis since 1971. Individual Home Secretaries are fully complicit in this dishonesty, most notably James Callaghan, Merlyn Rees, William Whitelaw, Leon Brittan, Douglas Hurd, Michael Howard, Jack Straw, Jacqui Smith, Alan Johnson and the incumbent, Theresa May.
Certainly in the last 20 years there can be no excuse at all. The balance of scientific evidence has been quite clear for at least that long that although a very small number of people may be vulnerable, for 99% of people cannabis is almost completely benign and often beneficial.
The dishonesty of these disgraced ministers brings shame on both the Conservative and Labour parties and the civil service officials in the Home Office. They all know full well that they have lied to the public and they continue to do so, undoubtedly because of corrupt influence from vested interests, principally the tabloid editors, press barons and the alcohol industry. Their lies have resulted in the unnecessary criminalisation of over one million people, the frittering away of tens of billions in futile law enforcement costs and lost tax revenue. Most dreadful of all, the denial of access to medicinal cannabis by those in pain, suffering and disability.
The basis for the government’s dismissal of the petition is given as the Advisory Council on the Misuse of Drugs (ACMD) 2008 report ‘Cannabis: Classification and Public Health’.
In the covering letter to the report, the then chair of the ACMD does say “… the use of cannabis is a significant public health issue. Cannabis can unquestionably cause harm to individuals and society.”
Judge for yourself whether the evidence in the report supports the idea that cannabis is a “significant public health issue”. I don’t think it does and nowhere in the report is such an unequivocal statement made except in the covering letter. Of course it is true that cannabis can cause harm to individuals, just as digestive biscuits, chips and sugary drinks can, so that’s pretty meaningless. There is no evidence in the report at all of cannabis causing harm to society.
But the covering letter then makes the point very strongly that “strategies designed to minimise its use and adverse effects must be predominantly public health ones. Criminal justice measures – irrespective of classification – will have only a limited effect on usage.”
The report recommends that cannabis remain in class C of the Misuse of Drugs Act 1971 but the government of the day, led by Gordon ‘Skunk is Lethal’ Brown, ignored that and increased it to class B.
Read the report yourself. Compare it with the government’s response to the petition. To claim that the report supports present policy is false. It directly contradicts present policy. There is also now a host of high quality evidence on the reality of decriminalised or regulated cannabis markets from the Netherlands, Portugal, Colorado and Washington. This shows beyond any doubt that the government’s suggestions of “drug dependence… misery… increased misuse” have no basis in evidence at all. Furthermore the idea that new tax revenue would be outweighed by new costs is directly contradicted by every study on the subject. I repeat, the government’s response is a pack of lies
Sadly, the United Kingdom is a country where government ministers are prepared to lie, mislead, distort evidence and deceive the British people in order to maintain policies based on prejudice and the corrupt influence of vested interests.
Across social media, it’s ‘on message’ to despise Big Pharma and to promote the idea that government and pharmaceutical companies are engaged in the business of making people ill and feeding them with drugs in the pursuit of profit.
In the cannabis campaign, it’s virtually compulsory to abuse, defame and promote conspiracy theories about GW Pharmaceuticals, the world’s leading developer of cannabis-based medicines.
Now GW Pharma is hardly ‘Big Pharma’. It’s annual revenues for 2014 were £30 million. By contrast, Pfizer’s 2014 revenue was $50 billion. But such trifling facts are of no concern to the keyboard warriors and trolls that plague the cannabis campaign and bring it into disrepute every day.
In any case, I’m not sure whose message this is and why anyone buys into this hate-filled invective and unjust condemnation of an industry that has saved so many lives. Antibiotics, vaccines and, yes, chemotherapy products have saved or extended millions of lives. The most profitable pharmaceutical product of all time, Zantac (ranitidine), cures or prevents stomach ulcers and has prevented millions from having to undergo major surgery. Certainly, as in any industry, there have been mistakes, things have gone wrong and much could be improved but overall, the pharmaceutical industry is a huge force for good in our world.
Those engaged in these bitter, vindictive, online campaigns are largely sheep, ignorant of the facts and simply jumping on another hysterical bandwagon that they understand nothing about. They complain about the pursuit of profit and that money is being made from medicines and healthcare. It’s a strangely socialist and anti-business attitude, particularly as so much of it comes from America, supposedly the home of free enterprise where the maverick and outsider who triumphs against all the odds is usually revered.
Dr Geoffrey Guy, who founded GW Pharmaceuticals in 1998, is such a man. He has broken the UK government’s prohibition of cannabis by outwitting a regulatory process run by the Home Office and the Medicines and Healthcare Products Regulatory Agency (MHRA) that is corrupt, dishonest and denies scientific evidence. In my view, he deserves great admiration and should be seen as a hero by cannabis campaigners, not as the villain that he is often portrayed.
Now, both GW’s lead products, Sativex and Epidiolex, look set to gain FDA approval in the US. This will be a fantastic achievement for Dr Guy and all his colleagues. It’s also something that we Britons should be immensely proud about. Even though America is a very long way ahead of us in understanding and using cannabis as medicine, it is British science and expertise that is breaking down US federal prohibition. Soon most Americans will have state sanctioned access to medical marijuana but also the option for doctor-prescribed cannabinoid medicine of unparalleled quality and consistency.
Of course, for now GW Pharma stands against the use of raw herbal cannabis and at present that’s a rational business decision but I won’t be at all surprised if in future it moves into that market too. There are already unconfirmed rumours that GW is considering entering the CBD market.
This is a story of enormous courage, innovation and triumph against all the odds. It is in the finest tradition of British ingenuity and business skill. Since the Middle Ages we have led the world in engineering, science and technology. Geoffrey Guy is another world leader from Britain, this small island that has given birth to so many. Surely, at least a knighthood, possibly a Nobel prize must be coming his way soon. Even if the curmudgeonly, loud mouthed critics of today attack him, in future years he will be seen as a great pioneer of medicine and he will deserve his place in history.
It seems that unless you choose a herbal product with a THR mark you can have no certainty at all about what you are buying.
An excellent report on the BBC’s ‘Trust Me I’m A Doctor‘, reveals that the industry is rife with confidence tricksters, fraudsters and probably some well-meaning incompetents. How can you know what you’re getting in a herbal product? This has major implications for the medicinal use of cannabis and the businesses that will be needed to supply the product when it is legally available.
The THR mark is Traditional Herbal Registration as regulated by the Medicines and Healthcare products Regulatory Agency (MHRA). It costs between £600 to £8000 to apply but that’s only if you’re claiming “the medicine is used for minor health conditions where medical supervision is not required (eg a cold).” If you want to claim anything more you have to apply for a marketing authorisation when fees are in excess of £100,000, plus the cost of clinical trials or evidence of your claims and your product’s safety.
This is probably the biggest single problem facing the campaign for medicinal cannabis. We are a round peg which doesn’t fit into any of the government’s square holes.
If we argue for cannabis as medicine, we challenge the reductionist, allopathic establishment which says that medicines are single molecules with directly quantifiable, predictable and consistent results. We cannot fit into the government’s square holes without the sort of approach taken by GW Pharmaceuticals at a cost of tens of millions in development.
That is why the campaign has to focus on removing cannabis from schedule 1, so that doctors may prescribe it as they see fit. Some doctors are ready to do so (a few brave individuals already are prescribing) but it will require a huge campaign to educate others as to why and how to prescribe – and it will not be possible to make any medical claims in that campaign!
The model of cannabis as medicine with different strains providing different therapeutic value just doesn’t fit within any concept of medicine in the UK. That’s like a triangular peg in a square hole.
So perhaps there is little point in an unwinnable campaign to legalise such a drug as medicine when its use is already tarnished by years of propaganda and media scaremongering? It may be a hopeless cause and seeking a more general decriminalisation of the plant might be a wiser course.
This is a question that seems to be unique to the UK. Other jurisdictions, such as the US states, have achieved reform through radical democracy which we do not enjoy in Britain. Canadians have used their courts to enforce access to cannabis as a fundamental human right. Other European countries just seem to be more flexible, intelligent and sympathetic to patients.
On the other hand, it does seem that the MHRA’s THR scheme works and you know what you are getting when you buy a herbal medicine. Otherwise charlatans and confidence tricksters would prevail.
These issues concern not only the campaign for medicinal cannabis but for cannabis law reform as a whole. Until we get to grips with them and develop a coherent approach we may find the UK continues to lag behind the rest of the world.